Production and characterization of metal nanoparticles for chemical reduction in order to application in biological systems

Background Several studies have demonstrated the use of metallic nanomaterials with applications in the biological area with very promising results. Gold nanoparticles (AuNP’s) have attracted great interest from researchers due to its electronic properties, optical, thermal, and its great potential for application in physical, chemical and biological [1]. In general, the AuNP’s are prepared by chemical reduction starting from a precursor (usually HAuCl4) is a strong reducing agent. The shape and size of the nanoparticles depend on the synthesis process variables such as concentration of the reactants, temperature, pH, reaction time, and others. The same material composition can be determined with different physical and chemical characteristics just modifying characteristics such as size, self-organization, crystalline structure and shape, the point of the material in the nanometer range show distinct physical and chemical properties of materials on the macroscopic scale [2]. The aim of this work was to prepare and characterize gold nanoparticles using the method of chemical reduction with sodium borohydride (NaBH4) in order to evaluate the influence of the concentration of the reducing agent and the time of synthesis on the properties of NP’s. The proposal is to use the material generated to evaluate its bactericidal effect.